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Alyssa Ofstein

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Alyssa Ofstein is a Senior Content Program Manager at Microsoft, where she leads strategy and execution for generative AI safety and security enablement. With deep expertise in responsible innovation, Alyssa co-creates safer products by designing from the margins and preempting unconventional risks. She has assessed hundreds of AI systems, authored engineering guidance for Microsoft’s Secure Development Lifecycle and Responsible AI standards and launched training programs that empower teams to build responsibly. Her work bridges governance and technical depth, translating complex requirements into actionable design patterns and scalable resources. Alyssa thrives at the intersection of policy, engineering, and strategic clarity, enabling confident and safe AI development across enterprise environments.

Bio from: Microsoft Ignite 2025

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Talks & appearances

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Build Secure AI Agents: Microsoft’s Stack, Your Innovation
breakout
with Alyssa Ofstein (Microsoft) , Neta Haiby (Microsoft) , Harmony Mabrey (Microsoft - Artificial Generative Intelligence Safety & Security)

Learn how Microsoft secures agentic AI systems across the lifecycle. Discover design strategies and real-world tool examples—from Microsoft Security and Microsoft Foundry—to build safe, resilient agents aligned with Secure Future Initiative principles.