Zachary Ziegler

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OpenEvidence

Zachary Ziegler is the cofounder and CTO of OpenEvidence, the leading medical information platform. Designed from the ground up for medical professionals, OpenEvidence organizes and expands the world's medical knowledge to make it more useful, open, accessible, and understandable. Launched out of the Mayo Clinic Platform Accelerate, OpenEvidence has become the most rapidly adopted tool by physicians in history, now used by over 40% of US physicians in over 15,000 care centers across the United States. Before founding OpenEvidence, Ziegler was a PhD student at Harvard University, where he worked with Professor Sasha Rush and was awarded the National Science Foundation Graduate Research Fellowship. He completed his undergraduate studies at Cornell University, where he received the Barry Goldwater Scholarship.

Bio from: Microsoft Ignite 2025

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Microsoft Ignite 2025 1

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Building autonomous enterprise agents with reasoning

2025-11-20 · Microsoft Ignite 2025 Watch

breakout

with Naomi Moneypenny (Microsoft) , Ashish Agrawal (AWS) , Alexander Hughes (Microsoft) , Zachary Ziegler (OpenEvidence) , Jennifer Marsman (Office of the CTO)

Microsoft

This session will highlight autonomous agents powered by reasoning models. These agents can plan, execute, and adapt across tasks like lead scoring, content generation, and customer support. We’ll demo agentic workflows using these models and you will learn to build agents in Microsoft Foundry that are aligned with enterprise goals.