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Did you know that digestion in C. elegans follows a rhythmic pH cycle? In this episode, we explore how magic nanosensors uncover real-time intestinal pH oscillations inside these tiny nematodes. By mapping the gut’s acidic landscape, researchers reveal how proton pumps, digestion, and metabolism work together in a synchronised chemical dance—offering new insights for biomedicine and drug discovery.

🔍 Key Topics Covered: • How pH-sensitive nanosensors track acidity in living organisms • The real-time pH oscillations inside the C. elegans gut • The role of proton pumps and metabolism in digestion • How this discovery could impact gut health and biomedical research

📖 Based on the research article: “Mapping the Pharyngeal and Intestinal pH of Caenorhabditis elegans and Real-Time Luminal pH Oscillations Using Extended Dynamic Range pH-Sensitive Nanosensors” Veeren M. Chauhan, Gianni Orsi, Alan Brown, David I. Pritchard, Jonathan W. Aylott. Published in ACS Nano (2013). 🔗 Read it here: https://doi.org/10.1021/nn401856u

Join us as we uncover how pH-shifting nanosensors are revolutionising our understanding of digestion and metabolism!

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This podcast is generated with artificial intelligence and curated by Veeren. If you’d like your publication featured on the show, please get in touch.

📩 More info: 🔗 www.veerenchauhan.com 📧 [email protected]

Presenter: Jonathan Dance (Hydra)