This is the first book of its kind to specifically address the interface between environmental epidemiology and spatio-temporal modeling. The book links recent developments in spatio-temporal methodology with epidemiological applications. Drawing on real-life problems, it provides the tools required to exploit recent advances in methodology when assessing the health risks associated with environmental hazards. The text includes practical examples together with embedded R code, details of specific R packages, and other software, including WinBUGS/OpenBUGS and INLA.