In this episode, we explore how microgravity affects muscle structure and function, using Caenorhabditis elegans as a model organism. Spaceflight-induced muscle atrophy is a major challenge for astronauts, and understanding the molecular and genetic mechanisms behind these changes is key to developing countermeasures.

This discussion is based on the review article: “Advancing Insights into Microgravity-Induced Muscle Changes Using Caenorhabditis elegans as a Model Organism” Beckett LJ, Williams PM, Toh LS, Hessel V, Gerstweiler L, Fisk I, Toronjo-Urquiza L, Chauhan VM. Published in npj Microgravity (2024). 📖 Read the full paper: ⁠https://doi.org/10.1038/s41526-024-00418-z⁠

🔬 Learn how C. elegans provides unique insights into metabolic changes, gene expression, and protein regulation during spaceflight, offering potential strategies to counteract muscle degradation.

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📩 More info: 🔗 www.veerenchauhan.com 📧 [email protected]