Pharmaceutical Statistics Using SAS: A Practical Guide offers extensive coverage of cutting-edge biostatistical methodology used in drug development and the practical problems facing today's drug developers. Written by well-known experts in the pharmaceutical industry Alex Dmitrienko, Christy Chuang-Stein, and Ralph D'Agostino, it provides relevant tutorial material and SAS examples to help readers new to a certain area of drug development quickly understand and learn popular data analysis methods and apply them to real-life problems. Step-by-step, the book introduces a wide range of data analysis problems encountered in drug development and illustrates them using a wealth of case studies from actual pre-clinical experiments and clinical studies. The book also provides SAS code for solving the problems. Among the topics addressed are these:

drug discovery experiments to identify promising chemical compounds animal studies to assess the toxicological profile of these compounds clinical pharmacology studies to examine the properties of new drugs in healthy human subjects Phase II and Phase III clinical trials to establish therapeutic benefits of experimental drugs.

Additional features include a discussion of methodological issues, practical advice from subject-matter experts, and review of relevant regulatory guidelines. Most chapters are self-contained and include a fair amount of high-level introductory material to make them accessible to a broad audience of pharmaceutical scientists. This book will also serve as a useful reference for regulatory scientists as well as academic researchers and graduate students.

This book is part of the SAS Press program.

You have more information at hand about your business environment than ever before. But are you using it to “out-think” your rivals? If not, you may be missing out on a potent competitive tool. In Competing on Analytics: The New Science of Winning, Thomas H. Davenport and Jeanne G. Harris argue that the frontier for using data to make decisions has shifted dramatically. Certain high-performing enterprises are now building their competitive strategies around data-driven insights that in turn generate impressive business results. Their secret weapon? Analytics: sophisticated quantitative and statistical analysis and predictive modeling. Exemplars of analytics are using new tools to identify their most profitable customers and offer them the right price, to accelerate product innovation, to optimize supply chains, and to identify the true drivers of financial performance. A wealth of examples—from organizations as diverse as Amazon, Barclay’s, Capital One, Harrah’s, Procter & Gamble, Wachovia, and the Boston Red Sox—illuminate how to leverage the power of analytics.

Essential MATLAB for Engineers and Scientists, Third Edition, is an essential guide to MATLAB as a problem-solving tool. It presents MATLAB both as a mathematical tool and a programming language, giving a concise and easy-to-master introduction to its potential and power. Stressing the importance of a structured approach to problem solving, the text provides a step-by-step method for program design and algorithm development. It includes numerous simple exercises for hands-on learning, a chapter on algorithm development and program design, and a concise introduction to useful topics for solving problems in later engineering and science courses: vectors as arrays, arrays of characters, GUIs, advanced graphics, and simulation and numerical methods. The text is ideal for undergraduates in engineering and science taking a course on Matlab. Numerous simple exercises give hands-on learning A chapter on algorithm development and program design Common errors and pitfalls highlighted Concise introduction to useful topics for solving problems in later engineering and science courses: vectors as arrays, arrays of characters, GUIs, advanced graphics, simulation and numerical methods A new chapter on dynamical systems shows how a structured approach is used to solve more complex problems. Text and graphics in four colour

Reveal your inner business artist with Visio Turn your ideas into diagrams and drawings with Visio's stencils and templates If you have an idea you want to get down on electronic paper, Visio 2007 is for you, and so is this book! They're both flexible and user-friendly. Here's how to use Visio to capture ideas from simple to intricate, update data in a drawing with a single click, add and manipulate text, work with connectors, and more. Discover how to Create business, engineering, software, or network diagrams Format an entire drawing using themes Analyze "what-if" scenarios with PivotDiagrams Produce layered multipage drawings Save drawings to publish on the Web

A practical, step-by-step approach to making sense out of data Making Sense of Data educates readers on the steps and issues that need to be considered in order to successfully complete a data analysis or data mining project. The author provides clear explanations that guide the reader to make timely and accurate decisions from data in almost every field of study. A step-by-step approach aids professionals in carefully analyzing data and implementing results, leading to the development of smarter business decisions. With a comprehensive collection of methods from both data analysis and data mining disciplines, this book successfully describes the issues that need to be considered, the steps that need to be taken, and appropriately treats technical topics to accomplish effective decision making from data. Readers are given a solid foundation in the procedures associated with complex data analysis or data mining projects and are provided with concrete discussions of the most universal tasks and technical solutions related to the analysis of data, including: Problem definitions Data preparation Data visualization Data mining Statistics Grouping methods Predictive modeling Deployment issues and applications Throughout the book, the author examines why these multiple approaches are needed and how these methods will solve different problems. Processes, along with methods, are carefully and meticulously outlined for use in any data analysis or data mining project. From summarizing and interpreting data, to identifying non-trivial facts, patterns, and relationships in the data, to making predictions from the data, Making Sense of Data addresses the many issues that need to be considered as well as the steps that need to be taken to master data analysis and mining.

Written for anyone involved in the data preparation process for analytics, Gerhard Svolba's Data Preparation for Analytics Using SAS offers practical advice in the form of SAS coding tips and tricks, and provides the reader with a conceptual background on data structures and considerations from a business point of view. The tasks addressed include viewing analytic data preparation in the context of its business environment, identifying the specifics of predictive modeling for data mart creation, understanding the concepts and considerations of data preparation for time series analysis, using various SAS procedures and SAS Enterprise Miner for scoring, creating meaningful derived variables for all data mart types, using powerful SAS macros to make changes among the various data mart structures, and more!

A new edition of this title is available, ISBN-10: 0321580303 ISBN-13: 9780321580306 The second of a two-book series about business intelligence and reporting technology, introduces programmers to BIRT architecture and the reporting framework. Built on the Eclipse platform, this exciting technology makes it possible for programmers to build and deploy customized reports using scripting and BIRT APIs. In addition, programmers can extend the BIRT framework by building new plug-ins using the Eclipse Plug-in Development Environment. Integrating and Extending BIRT This book describes the key components of BIRT architecture, applications, and engines, including installing, deploying, and troubleshooting the Reporting and Charting engines in an Enterprise Java application-server environment.For developers who wish to incorporate custom business logic in their reports or access data from Java objects, the book describes BIRT's extensive scripting capabilities in JavaScript and Java. For developers who want to extend the BIRT framework, the book describes the key extension points to use in creating customized report items, rendering extensions for generating output other than HTML or PDF, and Open Data Access (ODA) drivers for new data sources. The book provides extensive examples of how to build plug-ins to extend the features of the BIRT framework. Topics discussed include Installing and deploying BIRT Deploying a BIRT report to an application server Understanding BIRT architecture Scripting in a BIRT report design Integrating BIRT functionality in applications Working with the BIRT extension framework

The second edition of Business Statistics, continues to retain the clear, crisp pedagogy of the first edition. It now adds new features and an even stronger emphasis on practical, applied statistics that will enhance the text's ability in developing decision-making ability of the reader. In this edition, efforts have been made to assist readers in converting data into useful information that can be used by decision-makers in making more thoughtful, information-based decisions.

You'll gain a world of knowledge through Phil Mason's inventive tips and techniques. Updated and expanded to cover the breadth of functionality offered in SAS 8 and SAS 9, In the Know...SAS Tips and Techniques From Around the Globe, Second Edition, is packed with timeless classics and plenty of new material addressing such popular topics as the DATA step, SQL, macros, functions, ODS, and much more. Each tip is presented in a self-contained format that is both informative and easy to use. Every chapter contains a collection of related tips with frequent use of code and log examples to help improve productivity. Users of all levels will discover how to save time and effort by incorporating the wisdom found in these practical tips.

The authorized guide to the latest edition of the #1 business intelligence software product - Crystal Reports. More than 16 million licenses of Crystal Reports have been shipped to date. This book is a reference designed to provide hands-on guidance for the latest release of the product suite. The latest version of Crystal Reports and the Business Objects enterprise reporting suite delivers vast product enhancements and a tighter integration that will drive upgrades from licensees. Brand new features (e.g. Dynamic and Cascading Parameter Generation) will also appeal to new audiences. Over 1 million new Business Intelligence licensees will be migrating to the Crystal Enterprise Reporting platform, as this is the first release of the software with the existing Business Objects (BO) products being integrated into the Crystal infrastructure. As Business Objects insiders, the authors bring unique and valuable real-world perspectives on implementations and uses of the Crystal Reports product. The book also includes content, tutorials and samples for reporting within the Microsoft Visual Studio.NET and J2EE development environments and also on top of the SAP Business Information Warehouse (BW) and the Peoplesoft platform. Advanced content on report distribution and integration into the secured managed reporting solution known as Business Objects Enterprise XI, is also now included in this definitive user guide with coverage on the new Web Services SDK.

A new edition of this title is available, ISBN-10: 0321580273 ISBN-13: 9780321580276 The first in a two-book series about Business Intelligence and Reporting Technology, introduces reporting to a broad base of users. Built on the Eclipse platform, this exciting technology makes it possible for programmers and non-programmers to build and deploy complex reports with minimal effort. BIRT: A Field Guide to Reporting presents information about how to develop and customize reports of progressive complexity using BIRT Report Designer. This tool was designed from the ground up for Web applications and uses a Web page-oriented design metaphor in contrast to older banded report writers that were developed before the advent of the Internet. This unique approach to report creation makes BIRT an approachable and effective tool for developers of all levels. BIRT: A Field Guide to Reporting Report designs discussed include Listing reports that include sorting, grouping, and totals Summary reports, such as top N reports Charts, including pie, line, bar, and gauge charts Master-detail reports Other topics discussed include Understanding the technology Planning report designs Accessing data Laying out and formatting reports Building charts Enhancing reports with interactive viewing, shared libraries, and localized text Preparing reports for international data

The field of statistics is broad and complex, but this Infoline will help training professionals use statistics to execute their jobs even better. Why statistics? First, they allow you to make better decisions because data can be analyzed using proven mathematical principles and logic. Second, data are generated each moment across all business functions, and statistics allows the trainer quickly relate to business processes. Third, repetition is important for learner comprehension, and incorporating statistics and measures into training delivery helps learners acquire knowledge better and faster. And finally, the judicious use of statistics in presentations is a powerful way to support your case at higher organizational levels

In this IBM Redbooks publication, we describe and demonstrate how to implement enterprise performance insight. This is an initiative that has a primary focus on the integration of Business Process Management and Business Intelligence. With this capability, management has an enterprise-wide view of their business that can enable proactive business management. We discuss the techniques, architectures, and processes used to define and implement such an environment. Among the specific techniques and technologies used are key performance indicators, process alerts, management dashboards, analytic applications, application integration, process modeling and monitoring, and real-time business intelligence. The products featured are DB2 UDB, DB2 Alphablox, WebSphere Information Integrator, WebSphere Portal, WebSphere Business Monitor, and WebSphere Business Modeler. Performance insight is an element of a more global initiative called business innovation and optimization (BIO). With this, we can enable business performance management, an initiative for the effective use of people, processes, assets, and technology to proactively achieve business goals and measurements. It enables strategic alignment of business and technology, resulting in real-time access to data and continuous process and data flow, for proactive business management, and business goal attainment.

Learning to use SAS Enterprise Guide has never been easier! With The Little SAS Book for Enterprise Guide 4.1, Susan Slaughter and Lora Delwiche help you quickly become familiar with the SAS Enterprise Guide point-and-click environment. A series of carefully designed tutorials help you master the basics of the tasks you will want to do most frequently. The reference section of the book expands on the tutorial topics, focusing on specific features. If you are new to SAS or new to SAS Enterprise Guide, this book will be an invaluable tool on your way to becoming an expert.

The essentials of regression analysis through practical applications Regression analysis is a conceptually simple method for investigating relationships among variables. Carrying out a successful application of regression analysis, however, requires a balance of theoretical results, empirical rules, and subjective judgement. Regression Analysis by Example, Fourth Edition has been expanded and thoroughly updated to reflect recent advances in the field. The emphasis continues to be on exploratory data analysis rather than statistical theory. The book offers in-depth treatment of regression diagnostics, transformation, multicollinearity, logistic regression, and robust regression. This new edition features the following enhancements: Chapter 12, Logistic Regression, is expanded to reflect the increased use of the logit models in statistical analysis A new chapter entitled Further Topics discusses advanced areas of regression analysis Reorganized, expanded, and upgraded exercises appear at the end of each chapter A fully integrated Web page provides data sets Numerous graphical displays highlight the significance of visual appeal Regression Analysis by Example, Fourth Edition is suitable for anyone with an understanding of elementary statistics. Methods of regression analysis are clearly demonstrated, and examples containing the types of irregularities commonly encountered in the real world are provided. Each example isolates one or two techniques and features detailed discussions of the techniques themselves, the required assumptions, and the evaluated success of each technique. The methods described throughout the book can be carried out with most of the currently available statistical software packages, such as the software package R.

Do you want to learn and ultimately master Google's web and software tools beyond what information can find through their help files? Well Googlepedia shows both casual end-users and professional web developers how to get the most out of the Google search site and Google's powerful tools. For web searchers, Googlepedia describes how Google indexes web pages and ranks search results, and provides step-by-step instructions on conducting both basic and advanced queries. All types of searches are presented, including searches of specific government and university web sites. Finally, webmasters and website developers learn how to submit their pages to Google for indexing, increase their search rankings, incorporate Google searches on their Web sites, and use Google's Adsense service to make money from any sized website. For all web users, Googlepedia shows how to use and master Google's web-based and software-based tools. Readers learn how to enhance their PC's operation with the Google Pack and Google Toolbar; map destinations, get driving directions, and find nearby businesses with Google Maps and Google Earth; find the best online bargains with Froogle; instant message other users with Google Talk; view web pages in other languages with Google Translate; create their own blogs with Blogger; use Google on their mobile phones; and much, much more.

No one wants to end life's journey wondering: Did my life count for something? Did I have a reason for being here? The stories in this book show that for people of all ages, income levels, and expertise, the answer can be a resounding " Yes!" From extraordinary examples -- relief efforts in the aftermath of Hurricane Katrina or work in refugee camps in Afghanistan -- to localized, everyday actions, the authors demonstrate that living a life of service to others, and seeing how lives are changed as a result, establishes the meaning and significance all humans long for. Moreover, the book provides strategies for creating a purposeful life through daily service. The authors prove that the ability to find fulfillment is within reach, and that the discovery is waiting to be made in homes, workplaces, communities, neighborhoods, and schools all across America.

This title provides the most important theoretical aspects of Image and Signal Processing (ISP) for both deterministic and random signals. The theory is supported by exercises and computer simulations relating to real applications. More than 200 programs and functions are provided in the MATLAB® language, with useful comments and guidance, to enable numerical experiments to be carried out, thus allowing readers to develop a deeper understanding of both the theoretical and practical aspects of this subject.

Transform data into action for competitive advantage "The knowledge assets of an organization are becoming increasingly important for competitive advantage, and therefore, the way in which knowledge is created, renewed, and communicated is critical. This book provides practical insights into how this may be achieved through the establishment of a Business Intelligence Competency Centre and is a valuable read for 'information professionals.'" --Bill Sturman, Information Architecture Project Manager The Open University, United Kingdom "BI is more than technology and projects. BI must live in the organization--as a BICC. This book helps to make BI tangible and understandable, bringing it to life." --Miriam Eisenmann, Project Manager (PMP) CSC Ploenzke AG, Germany "This book is a must-read for planning and implementing your BICC. It is a pragmatic guide that addresses a lot, if not all, of the questions you'll be asking yourself. Don't miss out on getting a head start from the people who thought this through from start to finish . . . Pray your competitors don't get hold of this book!" --Claudia Imhoff, President Intelligent Solutions, Inc., USA "Creating a BICC forces the organization to focus on the importance of centralizing the gathering, interpreting, and analyzing of information to create business insight." --Anne Ulyate, Group Manager Business Intelligence Mutual & Federal, South Africa "BI is a highly visible element in the 'business value' trend for IT investments. Initiatives, such as competency centers, should empower user organizations to drive even more value out of their BI investments." --Marianne Kolding, Director, European ServicesIDC, United Kingdom

Want to calculate the probability that an event will happen? Be able to spot fake data? Prove beyond doubt whether one thing causes another? Or learn to be a better gambler? You can do that and much more with 75 practical and fun hacks packed into Statistics Hacks. These cool tips, tricks, and mind-boggling solutions from the world of statistics, measurement, and research methods will not only amaze and entertain you, but will give you an advantage in several real-world situations-including business. This book is ideal for anyone who likes puzzles, brainteasers, games, gambling, magic tricks, and those who want to apply math and science to everyday circumstances. Several hacks in the first chapter alone-such as the "central limit theorem,", which allows you to know everything by knowing just a little-serve as sound approaches for marketing and other business objectives. Using the tools of inferential statistics, you can understand the way probability works, discover relationships, predict events with uncanny accuracy, and even make a little money with a well-placed wager here and there. Statistics Hacks presents useful techniques from statistics, educational and psychological measurement, and experimental research to help you solve a variety of problems in business, games, and life. You'll learn how to: Play smart when you play Texas Hold 'Em, blackjack, roulette, dice games, or even the lottery Design your own winnable bar bets to make money and amaze your friends Predict the outcomes of baseball games, know when to "go for two" in football, and anticipate the winners of other sporting events with surprising accuracy Demystify amazing coincidences and distinguish the truly random from the only seemingly random--even keep your iPod's "random" shuffle honest Spot fraudulent data, detect plagiarism, and break codes How to isolate the effects of observation on the thing observed Whether you're a statistics enthusiast who does calculations in your sleep or a civilian who is entertained by clever solutions to interesting problems, Statistics Hacks has tools to give you an edge over the world's slim odds.